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Recent advances in gut microbiota-associated natural products: structures, bioactivities, and mechanisms.

Huan-Qin DaiJunjie HanTao WangWen-Bing YinYihua ChenHong-Wei Liu
Published in: Natural product reports (2023)
Covering: 2014 to June 2022The gut microbiota has attracted increasing attention from researchers due to its critical role in regulating human physiology and pathophysiology. Natural products (NPs) produced or transformed by gut microbes are key signalling mediators for a variety of physiological functions. On the other hand, NPs from ethnomedicines have also been found to generate health benefits through modulation of the gut microbiota. In this highlight, we review the most recent studies related to gut microbiota-derived NPs and bioactive NPs that regulate physiological and pathological processes via gut microbiota-associated mechanisms. We also outline the strategies for the discovery of gut microbiota-derived NPs and the methodologies of how to elucidate the crosstalk between bioactive NPs and the gut microbiota.
Keyphrases
  • healthcare
  • public health
  • endothelial cells
  • mental health
  • high resolution
  • high throughput
  • working memory
  • single cell
  • tissue engineering