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Cabozantinib versus everolimus, nivolumab, axitinib, sorafenib and best supportive care: A network meta-analysis of progression-free survival and overall survival in second line treatment of advanced renal cell carcinoma.

Billy AmzalShuai FuJie MengJohanna ListerHelene Karcher
Published in: PloS one (2017)
With all five families of distributions, cabozantinib was superior to all its comparators with a higher probability of longer PFS and OS during the analyzed 3 years, except with the Gompertz model, where nivolumab was preferred after 24 months.
Keyphrases
  • free survival
  • metastatic renal cell carcinoma
  • renal cell carcinoma
  • healthcare
  • palliative care
  • quality improvement
  • replacement therapy