Nickel-catalyzed regioselective hydrogen isotope exchange accelerated by 2-pyridones.

Zhi-Jiang JiangSi-Han XuYuhang SuErxun HuJiawei HanJian-Fei BaiBencan TangJia ChenZhanghua Gao

Published in: Chemical communications (Cambridge, England) (2023)

A nickel-catalyzed hydrogen isotope exchange has been developed with acetone- d 6 as the deuterium source. The reaction showed an improved kinetic feature of H/D exchange under the assistance of 2-pyridones, efficiently affording regioselective labeled aryl and alkyl carboxamides.

Keyphrases

room temperature
reduced graphene oxide
machine learning
visible light
ionic liquid
gas chromatography
carbon nanotubes
oxide nanoparticles
metal organic framework
computed tomography
high resolution