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Tumor and immune remodeling following radiotherapy in human renal cell carcinoma.

Jacky ChowAdil KhanMadeline GaudieriBrianna J WasikAlexis ConwayKah Teong SohElizabeth A RepaskyThomas SchwaabPaul K WallaceScott I AbramsElizabeth A RepaskyJason B Muhitch
Published in: Journal for immunotherapy of cancer (2023)
T-cell subsets and increased probability of interactions with tumor cells following standalone radiation treatment. This study provides a window into the irradiated tumor-immune microenvironment of patients and rationale for treatment combinations.
Keyphrases
  • renal cell carcinoma
  • stem cells
  • endothelial cells
  • clinical trial
  • ejection fraction
  • radiation therapy
  • end stage renal disease
  • early stage
  • squamous cell carcinoma
  • locally advanced
  • patient reported outcomes