No NFATC2 fusion in simple bone cyst of the jaw.
Sheena Li Ming OngIsadora Pereira GomesHans Jacobus BaeldeFabricio Passador-SantosBruno A B de AndradeInge H Briaire-de BruijnIsrael L CavalcanteWillem H SchreuderAnne-Marie Cleton-JansenArjen H G ClevenKároly SzuhaiCarolina C GomesJudith V M G BovéePublished in: Histopathology (2023)
In our study, NFATC2 rearrangement is absent in solitary jaw SBC (n = 7) and COD-associated SBC (n = 2). Our findings suggest that SBC presenting in the jaw is molecularly different from SBC in long bones. Future molecular studies may confirm the absence of clonal molecular aberrations in SBC of the jaw which would support a non-neoplastic, reactive origin.