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Genome-wide analysis identified abundant genetic modulators of contributions of the apolipoprotein E alleles to Alzheimer's disease risk.

Alireza NazarianYury LoikaLiang HeIrina CulminskayaAlexander M Kulminski
Published in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2022)
These findings suggest involvement of local and inter-chromosomal modulators of the effects of the APOE alleles on the AD risk.
Keyphrases
  • small molecule
  • genome wide analysis
  • cognitive decline
  • copy number
  • genome wide
  • metabolic syndrome
  • gene expression
  • dna methylation
  • breast cancer risk