Circulating bone morphogenetic protein 8A is a novel biomarker to predict advanced liver fibrosis.

Patricia MarañónStephania C IsazaCarlos Ernesto Fernández-GarcíaEsther ReyRocío Gallego-DuránRocío Montero-VallejoJavier Rodríguez de CíaJavier AmpueroÁngela M ValverdeManuel Romero-GómezCarmelo García-MonzónÁgueda González-Rodríguez

Published in: Biomarker research (2023)

This study provides experimental and clinical evidence indicating that BMP8A is a novel molecular target linked to liver fibrosis and introduces an efficient algorithm based on serum BMP8A levels to screen patients at risk for advanced hepatic fibrosis.

Keyphrases

liver fibrosis
end stage renal disease
mesenchymal stem cells
ejection fraction
newly diagnosed
machine learning
chronic kidney disease
high throughput
peritoneal dialysis
bone regeneration
patient reported outcomes
single cell
single molecule