Evaluating the Role of SNCA, LRRK2, and GBA in Chinese Patients With Early-Onset Parkinson's Disease.

Yongping Chen Xiaojing GuRuwei OuLingyu ZhangYanbing HouKuncheng LiuBei CaoQianqian WeiChunyu LiWei SongBi ZhaoYing WuJingqiu ChengHui Fang Shang

Published in: Movement disorders : official journal of the Movement Disorder Society (2020)

Our study provides a better understanding of the clinical and genetic correlations of α-synuclein, leucine-rich repeat kinase 2, and glucocerebrosidase in early-onset PD, which may be beneficial for drafting genetic scanning strategies and evaluating disease progression. © 2020 International Parkinson and Movement Disorder Society.

Keyphrases

early onset
late onset
genome wide
copy number
high resolution
electron microscopy