Less frequently mutated genes in colorectal cancer: evidences from next-generation sequencing of 653 routine cases.

Umberto MalapellePasquale PisapiaRoberta SgarigliaElena VigliarMaria BigliettoChiara CarlomagnoGiuseppe GiuffrèClaudio BellevicineGiancarlo Troncone

Published in: Journal of clinical pathology (2016)

In a routine diagnostic setting, NGS had the potential to generate robust and comprehensive genetic information also including less frequently mutated genes potentially relevant for prognostic assessments or for actionable treatments.

Keyphrases

genome wide
clinical practice
copy number
bioinformatics analysis
genome wide identification
wild type
healthcare
genome wide analysis
health information
risk assessment
social media
circulating tumor