Impact of Staging Concordance and Downstaging After Neoadjuvant Therapy on Survival Following Resection of Intrahepatic Cholangiocarcinoma: A Bayesian Analysis.
Laura AlaimoZorays MoazzamHenrique A LimaYutaka EndoSelamawit WoldesenbetAslam EjazJordan CloydAlfredo GuglielmiAndrea RuzzenenteTimothy M PawlikPublished in: Annals of surgical oncology (2023)
Patients with N1 ICC treated with NAT demonstrated improved OS compared with upfront surgery. Downstaging secondary to NAT conferred survival benefits among patients with cT3-4N1 versus upfront surgery. NAT should be considered in ICC patients with advanced T disease and/or nodal metastases.