Review of cerebral perfusion strategies for aortic surgery with application for minimally invasive approaches.
Ahmed AlnajarElizabeth F AleongMuhammad Z AzharRyan AzarrafiyJoseph LamelasPublished in: Journal of cardiac surgery (2020)
Aortic arch and hemiarch surgery necessitate the temporary interruption of blood perfusion to the brain. Despite its complexity, hemiarch and ascending aortic surgery can be performed via a minimally invasive approach. Due to the higher risk of neurological injury during a circulatory arrest, several techniques were developed to further protect the brain during this surgery. We searched the Embase, Medline, and Cochrane databases and identified articles reporting outcomes of antegrade and retrograde cerebral perfusion strategies. Herein, we outline surgical approaches, intra-operative technical considerations, and clinical outcomes of hemiarch and ascending aortic surgery. Hemiarch and ascending aortic surgery is associated with a higher risk of mortality and morbidity. Attention to the optimal approach and cerebral protection strategy has been shown to significantly affect outcomes and mitigate risk.
Keyphrases
- minimally invasive
- coronary artery bypass
- pulmonary artery
- robot assisted
- aortic valve
- left ventricular
- subarachnoid hemorrhage
- aortic dissection
- emergency department
- coronary artery
- machine learning
- cardiovascular disease
- white matter
- brain injury
- cell proliferation
- risk factors
- magnetic resonance
- metabolic syndrome
- multiple sclerosis
- cell cycle
- resting state
- artificial intelligence
- adipose tissue
- adverse drug
- deep learning
- cerebral blood flow