Optimization of the Diagnostic Capacity of Traditional Biomarkers in Muscle Damage and Its Use in the Diagnosis of Dermatomyositis and Polymyositis.

Sara Sanchez AsisMaría Cristina Gómez CoboDavid Ramos ChavarinoBeatriz García GarcíaIsabel Llompart AlbernJosé Antonio Delgado Rodríguez

Published in: EJIFCC (2024)

The determination of CK offers a better diagnostic performance of MD and, in addition, does not present significant differences regarding the determination of aldolase in cases of polymyositis and dermatomyositis. Therefore, the single determination of CK would be sufficient for MD screening.

Keyphrases

interstitial lung disease
systemic sclerosis
solid phase extraction
molecularly imprinted
rheumatoid arthritis
molecular dynamics
idiopathic pulmonary fibrosis
protein kinase
disease activity
oxidative stress
high resolution
liquid chromatography