A Virus-Infected, Reprogrammed Somatic Cell-Derived Tumor Cell (VIReST) Vaccination Regime Can Prevent Initiation and Progression of Pancreatic Cancer.

Shuangshuang LuZhe ZhangPan DuLouisa S ChardWenli YanMargueritte El KhouriZhizhong WangZhongxian ZhangYongchao ChuDongling GaoQinxian ZhangLirong ZhangAi NaganoJun WangClaude ChelalaJing LiuJiekai ChenPentao LiuChunguang QiuShengdian WangXiaozhu LiNicholas R LemoineDuanqing PeiYaohe Wang

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)

These results provide both proof of concept and a robust technology platform for the development of personalized prophylactic cancer vaccines to prevent pancreatic malignancies in at-risk individuals.

Keyphrases

papillary thyroid
single cell
squamous cell
cell therapy
copy number
bone marrow
young adults