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Transcriptional signatures differentiate pathogen- and treatment-specific host responses in patients with bacterial bloodstream infections.

Joshua T ThadenRichard AhnFelicia RuffinDavid W GjertsonAlexander HoffmannVance G FowlerMichael R Yeaman
Published in: The Journal of infectious diseases (2023)
Given importance of immune cellular energetics and reactive oxygen species in eliminating hematogenous or intracellular MRSA, these findings may offer insights into its persistence relative to other bacterial BSI.
Keyphrases
  • reactive oxygen species
  • staphylococcus aureus
  • gene expression
  • transcription factor
  • candida albicans
  • oxidative stress
  • combination therapy
  • replacement therapy
  • dna methylation