Microglia at Sites of Atrophy Restrict the Progression of Retinal Degeneration via Galectin-3 and Trem2 Interactions.

Chen YuEleonora M LadRose MathewSejiro LittletonYun ChenKai SchlepckowSimone DeganLindsey ChewJoshua AmasonJoan KalnitskyCatherine Bowes RickmanAlan D ProiaMarco ColonnaChristian HaassDaniel R Saban

Published in: bioRxiv : the preprint server for biology (2023)

A common neuroprotective response of microglia at the site of retinal atrophy is identified in mice and humans.

Keyphrases

optical coherence tomography
diabetic retinopathy
inflammatory response
neuropathic pain
optic nerve
high fat diet induced
type diabetes
skeletal muscle
wild type