Human X chromosome exome sequencing identifies BCORL1 as contributor to spermatogenesis.

Chuncheng LuYan ZhangYufeng QinQiaoqiao XuRan ZhouYiqiang CuiYunfei ZhuXin ZhangJintao ZhangXiang WeiMin WangBo HangJian-Hua MaoAntoine M SnijdersMingxi LiuZhibin HuHongbing ShenZuomin ZhouXuejiang GuoXin WuXinru WangYan-Kai Xia

Published in: Journal of medical genetics (2020)

Our data indicate that the X-linked genes are associated with male infertility and involved in regulating SSCs, which provides a new insight into the role of X-linked genes in spermatogenesis.

Keyphrases

genome wide
copy number
endothelial cells
bioinformatics analysis
dna methylation
genome wide identification
single cell
electronic health record
induced pluripotent stem cells
big data
genome wide analysis
type diabetes
gene expression
skeletal muscle
artificial intelligence