Relationship between hemoglobin A1c level and flow-mediated vasodilation in patients with type 2 diabetes mellitus receiving antidiabetic drugs.

Takayuki YamajiTakahiro HaradaYu HashimotoYukiko NakanoMasato KajikawaKenichi YoshimuraGaku AokiKazuaki ChayamaChikara GotoAya MizobuchiYiming HanFarina Mohamad YusoffShinji KishimotoTatsuya MaruhashiAyumu NakashimaYukihito Higashi

Published in: Journal of diabetes investigation (2021)

These findings suggest that a low HbA1c <6.5% as well as a high HbA1c ≥8.0% is associated with endothelial dysfunction in patients with type 2 diabetes mellitus who are receiving antidiabetic drugs and that vascular smooth muscle function is similar in such patients regardless of the HbA1c level.

Keyphrases

smooth muscle
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
patient reported outcomes
drug induced