Multidisciplinary therapy strategy of precision medicine in clinical practice.
Mengjia QianQian LiMiaomiao ZhangXiaojing XuQi ShenHao ChenXiangdong WangTianshu LiuYunfeng ChengPublished in: Clinical and translational medicine (2020)
The application of precision medicine concept in clinical work needs a period of practice and experience accumulation. The present article introduced an example of functioning approach named "multidisciplinary therapy strategy of precision medicine" (MDTS-PM), clinical practice and process, decision-making, and therapies. The MDTS-PM integrates multidisciplinary experts and develops real-time therapeutic strategy based on clinical phenomes and gene sequencing of tissue DNA and circulating DNA. The strength of MDTS-PM is the combination of dynamical clinical phenomes, genetic information, diagnosis, and treatment to make the therapy more targeted and specific. MDTS-PM provides comprehensive, whole-process, and personalized diagnosis and treatment services for patients with complex cancer or complex drug resistance progression; provides guidance for further adjustment of drug use; and establishes a multidisciplinary cooperative team, improves the quality of clinical diagnosis and treatment, and optimizes the process of medical services.
Keyphrases
- healthcare
- particulate matter
- clinical practice
- air pollution
- quality improvement
- primary care
- heavy metals
- decision making
- polycyclic aromatic hydrocarbons
- mental health
- palliative care
- genome wide
- circulating tumor
- copy number
- drug delivery
- single molecule
- gene expression
- social media
- risk assessment
- bone marrow
- health information
- young adults
- single cell
- water soluble
- lymph node metastasis