Characterised intron retention profiles in muscle tissue of idiopathic inflammatory myopathy subtypes.

Yizhi XiaoShasha XieHong-Dong LiYanjuan LiuHuali ZhangXiaoxia ZuoHonglin ZhuYisha LiHui Luo

Published in: Annals of the rheumatic diseases (2024)

This study revealed distinct IRs and specific splicing factors associated with IIM subtypes, which might be contributing to the pathogenesis of IIM. We also emphasised the potential impact of IR on protein expression in IIM muscles.

Keyphrases

skeletal muscle
oxidative stress
late onset
single cell
risk assessment
climate change
early onset
muscular dystrophy
myasthenia gravis