Induction of the immunoprotective coat of Yersinia pestis at body temperature is mediated by the Caf1R transcription factor.

Abdulmajeed D Al-JawdahIglika G IvanovaHelen WallerNeil D PerkinsJeremy H LakeyDaniel T Peters

Published in: BMC microbiology (2019)

The results show that thermal control of Caf1 polymer production is established at the transcriptional level, in a Caf1R dependent manner. This gives us new insights into how a virulent pathogen evades destruction by the immune system by detecting and responding to environmental changes.

Keyphrases

transcription factor
gene expression
dna binding
human health
risk assessment
climate change