COVID-19 disease is caused by a novel coronavirus (SARS-CoV-2), and it was declared as a pandemic by WHO within two and half months of detection of first case. The pandemic situation induced unprecedented cooperation amongst countries, academia, public sector institutions and industry in sharing knowledge, resources and strategies. In this article, development of vaccines and their delivery system is discussed. The regulatory toxicology and clinical trials are the most important factors to ensure safety and formation of neutralizing antibodies for efficacy. The article creates awareness about the global cooperation and efforts in developing the vaccines speedily for the society. Finally, results show that all the COVID-19 vaccines trigger an immune response to enable your body to fight and kill virus and none of them cause COVID-19 disease.