Paraneoplastic cerebellar degeneration: Yo antibody alters mitochondrial calcium buffering capacity.

Published in: Neuropathology and applied neurobiology (2018)

These findings suggest that minimizing intracellular calcium overload toxicity either directly with cyclosporin-A or indirectly with cannabidiol or the ROS scavenger butylated hydroxytoluene promotes mitochondrial calcium homeostasis and may therefore be used as future neuroprotective therapy for PCD patients.

Keyphrases

oxidative stress
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
reactive oxygen species
dna damage
peritoneal dialysis
prognostic factors
cell death
current status
cerebral ischemia
blood brain barrier