Free light chains of immunoglobulins in patients with systemic sclerosis: correlations with lung involvement and inflammatory milieu.
Silvia BoselloUmberto BasileEnrico De LorenzisFrancesca GulliGiovanni CanestrariCecilia NapodanoFederico ParisiKrizia PocinoClara Di MarioBarbara TolussoGianfranco FerraccioliElisa GremesePublished in: Journal of clinical pathology (2018)
FLC levels are elevated in SSc and high levels are associated with lung involvement and with a higher degree of inflammation, supporting a possible role of B cell activation in the pathophysiology of the disease.