Effect of Surgical Margin Width on Patterns of Recurrence among Patients Undergoing R0 Hepatectomy for T1 Hepatocellular Carcinoma: An International Multi-Institutional Analysis.
Diamantis I TsilimigrasKota SaharaDimitrios MorisJ Madison HyerAnghela Z ParedesFabio BaganteKatiuscha MerathAyesha S FarooqFrancesca RattiHugo P MarquesOlivier SoubraneDaniel AzoulayVincent LamGeorge A PoultsidesIrinel PopescuSorin AlexandrescuGuillaume MartelAlfredo GuglielmiTom HughLuca AldrighettiItaru EndoTimothy M PawlikPublished in: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract (2019)
Resection margins > 1 cm predicted better RFS among patients undergoing R0 hepatectomy for T1 HCC, especially small (< 5 cm) HCC. Although resection margin width did not influence outcomes after anatomic resection, wider margins were more important among patients undergoing non-anatomic liver resections.