Cortical Tau Aggregation Patterns associated with Apraxia in Alzheimer's Disease.

Gerard N BischofElena JaegerKathrin GiehlFrank JessenOezguer A OnurSid O'BryantEsra KaraPeter H WeissAlexander Drzezga

Published in: medRxiv : the preprint server for health sciences (2024)

These results suggest that tau deposition in specific cortical brain regions may induce local neuronal dysfunction leading to a dose-dependent functional decline in praxis performance.

Keyphrases

cerebrospinal fluid
cerebral ischemia
white matter
cognitive decline
resting state
oxidative stress
multiple sclerosis
brain injury
subarachnoid hemorrhage
mild cognitive impairment