99mTc-A1 as a Novel Imaging Agent Targeting Mesothelin-Expressing Pancreatic Ductal Adenocarcinoma.

Christopher MontemagnoShamir CassimDimitry TrichanhClara SavaryJacques PouyssegurGilles PagèsDaniel FagretAlexis BroisatCatherine Ghezzi

Published in: Cancers (2019)

99mTc-A1 accurately allows imaging of mesothelin-expressing experimental PDAC tumors. Our experiments paved the way for the development of a companion test for mesothelin-targeted therapies.

Keyphrases

high resolution
drug delivery
fluorescence imaging
photodynamic therapy
wild type