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Alpha-Lipoic Acid, Auraptene, and Particularly Their Combination Prevent the Metastasis of U87 Human Glioblastoma Cells.

Azam IzadiMohammad SoukhtanlooFarshad MirzaviMohammad Jalili-NikAsie Sadeghi
Published in: Evidence-based complementary and alternative medicine : eCAM (2023)
This study demonstrated that the combination of ALA and AUR effectively inhibited the migration and metastasis of U87 cells. Thus, given their safety and favorable specifications, the combination of these drugs can be a promising candidate for GBM treatment as primary or adjuvant therapy.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • endothelial cells
  • cell death
  • signaling pathway
  • endoplasmic reticulum stress
  • cell proliferation