Advances in Diagnosis and Management of Childhood Osteoporosis
David Boon Ngan LimRebecca Jane MoonJustin Huw DaviesPublished in: Journal of clinical research in pediatric endocrinology (2022)
Childhood osteoporosis leads to increased propensity to fracture, and thus is an important cause of morbidity, pain and healthcare utilisation. Osteoporosis in children may be caused by a primary bone defect or secondary to an underlying medical condition and/or its treatment. Primary osteoporosis is rare, but there is an increasing number of children with risk factors for secondary osteoporosis. Therefore it is imperative that all paediatricians are aware of the diagnostic criteria and baseline investigations for childhood osteoporosis to enable timely referral to a specialist in paediatric bone health. This review will discuss the approach to diagnosis, investigation and management of childhood osteoporosis, with particular consideration to advances in molecular diagnosis of primary bone disorders, and current and emerging therapies for fracture reduction.
Keyphrases
- bone mineral density
- postmenopausal women
- healthcare
- body composition
- young adults
- emergency department
- early life
- public health
- primary care
- chronic pain
- childhood cancer
- pain management
- mental health
- soft tissue
- risk assessment
- health information
- smoking cessation
- single molecule
- bone loss
- bone regeneration
- health insurance