Protection from systemic pyruvate at resuscitation in newborn lambs with asphyxial cardiac arrest.

Vasantha H S KumarSylvia GuginoLori NielsenPraveen ChandrasekharanCarmon KoenigsknechtJustin HelmanSatyan Lakshminrusimha

Published in: Physiological reports (2021)

Pyruvate promotes energy generation accompanied by efficient oxygen utilization in the brain and may facilitate additional neuroprotection in the presence of hypoxic-ischemic injury.

Keyphrases

cardiac arrest
cardiopulmonary resuscitation
cerebral ischemia
resting state
white matter
brain injury
functional connectivity
drug induced
septic shock