Tolerance to neurochemical and behavioral effects of the hallucinogen 25I-NBOMe.
Monika HerianMateusz SkawskiAdam WojtasMałgorzata K SobocińskaKarolina NoworytaKrystyna GołembiowskaPublished in: Psychopharmacology (2021)
Our findings suggest that multiple injections of 25I-NBOMe induce tolerance to hallucinogenic activity and produce alterations in neurotransmission. 25I-NBOMe effect on short-term memory, locomotor function, and anxiety seems to be the result of complex interactions between neurotransmitter pathways.