Inflamed immune phenotype predicts favorable clinical outcomes of immune checkpoint inhibitor therapy across multiple cancer types.
Jeanne ShenYoon-La ChoiTaebum LeeHyojin KimYoung Kwang ChaeBen W DulkenStephanie BogdanMaggie HuangGeorge A FisherSehhoon ParkSe-Hoon LeeJun-Eul HwangJin-Haeng ChungLeeseul KimHeon SongSergio PereiraSeunghwan ShinYoojoo LimChang Ho AhnSeulki KimChiyoon OumSukjun KimGahee ParkSanghoon SongWonkyung JungSeokhwi KimYung-Jue BangTony S K MokSiraj M AliChan-Young OckPublished in: Journal for immunotherapy of cancer (2024)
The AI-based IIP may represent a practical, affordable, clinically actionable, and tumor-agnostic biomarker prognostic of ICI therapy response across diverse tumor types.