Myogenic Differentiation of Stem Cells for Skeletal Muscle Regeneration.
Dengjie YuZijun CaiDaishi LiYi ZhangMiao HeYuntao YangDi LiuWen-Qing XieYuSheng LiWenfeng XiaoPublished in: Stem cells international (2021)
Stem cells have become a hot research topic in the field of regenerative medicine due to their self-renewal and differentiation capabilities. Skeletal muscle tissue is one of the most important tissues in the human body, and it is difficult to recover when severely damaged. However, conventional treatment methods can cause great pain to patients. Stem cell-based tissue engineering can repair skeletal muscle to the greatest extent with little damage. Therefore, the application of stem cells to skeletal muscle regeneration is very promising. In this review, we discuss scaffolds and stem cells for skeletal muscle regeneration and put forward our ideas for future development.
Keyphrases
- stem cells
- skeletal muscle
- insulin resistance
- tissue engineering
- cell therapy
- endothelial cells
- end stage renal disease
- gene expression
- ejection fraction
- chronic pain
- chronic kidney disease
- newly diagnosed
- pain management
- oxidative stress
- metabolic syndrome
- prognostic factors
- mesenchymal stem cells
- type diabetes
- bone marrow
- induced pluripotent stem cells