Forelimb Resistance Exercise Protects Against Neuromuscular Junction Denervation in the SOD1-G93A Rat Model of ALS.

Hiroshi NishimuneKimberly G StanfordJie ChenJames D OdumAlexander D RorieRobert S RogersJoshua L WheatleyPaige C GeigerJohn A Stanford

Published in: Degenerative neurological and neuromuscular disease (2022)

These results demonstrate that isometric resistance exercise may protect against NMJ denervation in ALS. Future studies are required to determine the extent to which our findings generalize to female SOD1-G93A rats and to other subtypes of ALS.

Keyphrases

amyotrophic lateral sclerosis
resistance training
high intensity
physical activity
body composition
current status
case control