An analysis of Y-chromosome microdeletion in infertile Korean men with severe oligozoospermia or azoospermia.

Tae Ho Lee Seung Hun Song Dae Keun Kim Sung Han Shim Daeun Jeong Dong Suk Kim

Published in: Investigative and clinical urology (2024)

Y-chromosome microdeletion is a common genetic cause of male infertility. Therefore, Y-chromosome microdeletion test is recommended for the accurate diagnosis of men with azoospermia or severe oligozoospermia. Appropriate genetic counseling is mandatory before the use of assisted reproduction technique in men with Y-chromosome microdeletion.

Keyphrases

copy number
middle aged
genome wide
early onset
polycystic ovary syndrome
high resolution
dna methylation
metabolic syndrome
gene expression
adipose tissue
type diabetes
mass spectrometry
smoking cessation