Risk of relapse of ANCA-associated vasculitis among patients homozygous for the proteinase 3 gene Val119Ile polymorphism.

Marta Casal MouraZuoming DengStephen R BrooksWei TewFernando C FervenzaCees G M KallenbergCarol A LangfordPeter A MerkelPaul A MonachPhilip SeoRobert F SpieraE William St ClairJohn H StoneMarco PrunottoPeter C GraysonUlrich Specks

Published in: RMD open (2023)

Ile polymorphism appears associated with higher frequency of severe relapse. Further studies are necessary to better understand the association of this observation with the risk of severe relapse.

Keyphrases

free survival
early onset
drug induced
genome wide
copy number
dna methylation
gene expression