Impact of body mass index on pathological complete response following neoadjuvant chemotherapy in operable breast cancer: a meta-analysis.

Haiyun WangShijia ZhangDouglas YeeSaonli BasuHeather BeckwithDavid PotterAnne H Blaes

Published in: Breast cancer (Tokyo, Japan) (2021)

Overweight and obese breast cancer patients had a lower pCR rate with NACT compared to patients with under-/normal weight. Further prospective studies may help confirm this finding and investigate possible mechanisms.

Keyphrases

neoadjuvant chemotherapy
body mass index
weight gain
locally advanced
lymph node
sentinel lymph node
physical activity
case control
rectal cancer
weight loss
radiation therapy
real time pcr