Login / Signup

Reorganization of the Flagellum Scaffolding Induces a Sperm Standstill During Fertilization.

Martina JabloñskiGuillermina M LuqueMatías D Gómez-ElíasClaudia Sanchez-CardenasXinran XuJose Luis de la Vega-BeltranGabriel CorkidiAlejandro LinaresVictor X Abonza AmaroDario KrapfDiego KrapfAlberto DarszonAdan GuerreroMariano Gabriel Buffone
Published in: bioRxiv : the preprint server for biology (2023)
In this work, we demonstrate that the helical structure of polymerized actin in the flagellum undergoes a rearrangement at the time of sperm-egg fusion. This process is driven by intracellular calcium and promotes a decrease in the sperm midpiece diameter as well as the arrest in motility, which is observed after the fusion process is initiated.
Keyphrases
  • cell cycle
  • optic nerve
  • cell proliferation
  • pseudomonas aeruginosa
  • cell migration
  • cystic fibrosis
  • optical coherence tomography