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Warthin-Finkeldey giant cells-A useful clue for the cytodiagnosis of Kimura disease: A report of three cases.

Kanchan KothariMona A AgnihotriAmey RojekarTejaswini WaghmareAshvini Kolhe
Published in: Diagnostic cytopathology (2020)
Kimura disease (KD) is a rare, idiopathic chronic inflammatory disorder that usually presents as unilateral painless lymphadenopathy or soft tissue swelling of the head and neck region in young Asian males. The disease lacks pathognomonic clinical and cytomorphological features and can be mistaken for many reactive and malignant conditions. We report three cases of KD presenting as bilateral swelling of the head and neck region, and describe the cytomorphological features of each. In the correct clinical setting, a polymorphous lymphoid aspirate with eosinophils and Warthin-Finkeldey giant cells should raise a suspicion of KD and prompt further work up.
Keyphrases
  • middle aged
  • induced apoptosis
  • cell cycle arrest
  • soft tissue
  • oxidative stress
  • cell death
  • signaling pathway
  • cell proliferation
  • case report