CCL2 is associated with microglia and macrophage recruitment in chronic traumatic encephalopathy.

Jonathan D CherryGaoyuan MengSarah DaleyWeiming XiaSarah SvirskyVictor E AlvarezRaymond NicksMorgan PothastHunter KelleyBertrand HuberYorghos TripodisMichael L AloscoJesse MezAnn C McKeeThor D Stein

Published in: Journal of neuroinflammation (2020)

Overall, CCL2 is implicated in the pathways recruiting microglia and the development of pTau pathology after exposure to RHI, and may represent a future therapeutic target in CTE.

Keyphrases

liver injury
inflammatory response
liver fibrosis
neuropathic pain
drug induced
spinal cord injury
current status
adipose tissue
early onset
spinal cord