Homocysteine, folic acid, and vitamin B12 levels in patients on isotretinoin therapy for acne vulgaris: A meta-analysis.
Hyun-Jung KimSeung Min LeeJong Suk LeeSung Yul LeeEuy Hyun ChungMoon Kyun ChoSang Hoon LeeJung Eun KimPublished in: Journal of cosmetic dermatology (2019)
This meta-analysis found that Iso therapy was associated with changes in plasma levels of Hcy and folic acid in acne patients. However, further evaluation in controlled studies is needed to verify these results.