Exploring the functionality of fluorescent liposomes in cancer: diagnosis and therapy.
Bhupendra Gopalbhai PrajapatiJai Bharti SharmaAshutosh PareekRahul GargPushpendra Kumar SainiDevesh U KapoorPublished in: Zeitschrift fur Naturforschung. C, Journal of biosciences (2024)
Fluorescent liposomes are pivotal in cancer research, serving as adaptable vehicles for imaging and therapeutics. These small lipid vesicles, capable of encapsulating fluorescent dyes, offer precise visualization and monitoring of their targeted delivery to cancer cells. This review delves into the critical role fluorescent liposomes play in enhancing both cancer diagnosis and treatment. It provides an in-depth analysis of their structural features, fluorescent labeling techniques, targeting strategies, and the challenges and opportunities they present. In the domain of cancer diagnosis, the article sheds light on various imaging modalities enabled by fluorescent liposomes, including fluorescence imaging and multimodal techniques. Emphasis is placed on early detection strategies, exhibiting the utility of targeted contrast agents and biomarker recognition for enhanced diagnostic precision. Moving on to cancer treatment, the review discusses the sophisticated drug delivery mechanisms facilitated by fluorescent liposomes, focusing on chemotherapy and photodynamic therapy. Moreover, the exploration extends to targeted therapy, explaining the applications of fluorescent liposomes in gene delivery and RNA interference. In a nutshell, his article comprehensively explores the multifaceted impact of fluorescent liposomes on advancing cancer diagnosis and treatment, combining existing knowledge with emerging trends.
Keyphrases
- drug delivery
- quantum dots
- living cells
- papillary thyroid
- photodynamic therapy
- drug release
- cancer therapy
- fluorescence imaging
- squamous cell
- label free
- healthcare
- magnetic resonance
- stem cells
- magnetic resonance imaging
- high resolution
- fluorescent probe
- mesenchymal stem cells
- radiation therapy
- computed tomography
- young adults
- pain management
- rectal cancer
- optical coherence tomography
- contrast enhanced