Ingestion poisoning related lung injury- a pictorial review.
Rishabh JainAshu Seith BhallaPriyanka NaranjeSurabhi VyasVimi RewariIrshad Ahmad BandayManisha JanaPublished in: Emergency radiology (2022)
Poison ingestion is a medical emergency requiring immediate care in the emergency department. Respiratory symptoms with ingested poisons can occur due to aspiration, cardiopulmonary effects, or direct lung toxicity due to injury of the alveolar epithelium. Chest imaging (chest radiographs/CT) is usually performed in the emergency setting to evaluate such symptoms. It is often impossible to elicit the nature of the poison ingested by the patients due to their unconscious state. Identification of the culprit poison can expedite the patient's management towards a specific antidote or help understand the underlying mechanism causing the pulmonary symptoms. The imaging manifestations depend on the underlying mechanisms, varying for each ingested poison, forming an imaging signature which has not been adequately discussed in existing literature. Poisons like paraquat and organophosphate are important to differentiate as indiscriminate use of oxygen therapy in the former can exacerbate the lung injury caused by redox cycling. In this pictorial assay, we present the chest imaging spectrum of commonly ingested poisons, and further suggest algorithmic approach towards identification of common poisons based on their chest imaging.
Keyphrases
- emergency department
- high resolution
- healthcare
- public health
- end stage renal disease
- systematic review
- computed tomography
- chronic kidney disease
- magnetic resonance imaging
- oxidative stress
- stem cells
- palliative care
- case report
- sleep quality
- bone marrow
- prognostic factors
- fluorescence imaging
- patient reported outcomes
- mass spectrometry
- ultrasound guided
- drug induced