Associations of hyponatremia and SIADH with increased mortality, young age and infection parameters in patients with tuberculosis.
Christina BalDaniela GompelmannMichael KrebsLukasz AntoniewiczClaudia Guttmann-DuckeAntje LehmannChristopher Oliver MilacekMaximilian Robert GysanPeter WolfMaaia-Margo JentusIrene SteinerMarco IdzkoPublished in: PloS one (2022)
In this study of a large cohort from a tertiary care hospital in a non-endemic area of TB, 0.07% of patients presenting with hyponatremia, but especially younger patients and patients with high CRP values, were diagnosed with TB. Crucially, patients with moderate to profound hyponatremia had a significantly higher mortality rate and thus required increased medical care.
Keyphrases
- mycobacterium tuberculosis
- end stage renal disease
- cardiovascular events
- ejection fraction
- newly diagnosed
- chronic kidney disease
- risk factors
- peritoneal dialysis
- emergency department
- high intensity
- hiv aids
- pulmonary tuberculosis
- autism spectrum disorder
- atrial fibrillation
- human immunodeficiency virus
- adverse drug