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Clinical significance of intratumoral HER2 heterogeneity on trastuzumab efficacy using endoscopic biopsy specimens in patients with advanced HER2 positive gastric cancer.

Shusuke YagiTakeru WakatsukiNoriko YamamotoKeisho ChinDaisuke TakahariMariko OguraTakashi IchimuraIzuma NakayamaHiroki OsumiEiji ShinozakiMitsukuni SuenagaJunko FujisakiYuichi IshikawaKensei YamaguchiKen NamikawaYusuke Horiuchi
Published in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (2018)
Similar to surgical specimens, we verified clinical significance of HER2 heterogeneity on trastuzumab efficacy using endoscopic biopsy specimens.
Keyphrases
  • ultrasound guided
  • fine needle aspiration
  • epidermal growth factor receptor
  • single cell
  • metastatic breast cancer