Cell sheets of human dental pulp stem cells for future application in bone replacement.
Ana Clara Fagundes PedroniGiovanna SarraNatacha Kalline de OliveiraMaria Stella MoreiraMaria Cristina Zindel DeboniMárcia Martins MarquesPublished in: Clinical oral investigations (2018)
Cell sheets of hDPSCs could be employed as natural tri-dimensional structures for treating bone loss. This technique would be useful particularly for critical bone defects or any type of bone defects in patients carrying diseases that impair bone regeneration, such as diabetes mellitus, medication-related osteonecrosis of the jaw (MRONJ), and osteoporosis.
Keyphrases
- bone loss
- bone regeneration
- bone mineral density
- stem cells
- cell therapy
- single cell
- postmenopausal women
- end stage renal disease
- ejection fraction
- chronic kidney disease
- endothelial cells
- newly diagnosed
- soft tissue
- healthcare
- adipose tissue
- emergency department
- mesenchymal stem cells
- patient reported outcomes
- bone marrow
- induced pluripotent stem cells
- adverse drug