Isolated cerebellar stroke in a paediatric patient with typical haemolytic uraemic syndrome: a case report and literature review.
Manuela Lo BiancoSergio RinellaFelice D'ArcoEvangelia IoannidouMarios KaliakatsosPublished in: Neuroradiology (2024)
Haemolytic Uraemic Syndrome (HUS) is a rare medical condition characterised by microangiopathic haemolytic anaemia, thrombocytopenia, and acute kidney injury. Neurological complications are documented but rarely involve the cerebellum. We present a unique case of a 23-month-old male with HUS triggered by Escherichia coli-O157 (E.coli-O157) infection leading to an isolated cerebellar stroke.The patient initially presented with fever, bloody stools, and seizures. Confirmation of E.coli-O157 infection was obtained, and MRI revealed an isolated cerebellar stroke. Treatment included supportive care, anticoagulation for a right atrial thrombus, with gradual improvement observed.This case highlights the unusual occurrence of isolated cerebellar stroke in HUS patients, emphasising the importance of promptly recognizing manifestations of the central nervous system and the necessity for a multidisciplinary approach. Finally, a comprehensive literature review was conducted to identify cases of HUS patients with cerebellar involvement.
Keyphrases
- atrial fibrillation
- escherichia coli
- case report
- acute kidney injury
- healthcare
- end stage renal disease
- cerebral ischemia
- magnetic resonance imaging
- quality improvement
- intensive care unit
- heart failure
- chronic kidney disease
- emergency department
- peritoneal dialysis
- venous thromboembolism
- risk assessment
- computed tomography
- cerebrospinal fluid
- biofilm formation
- klebsiella pneumoniae
- subarachnoid hemorrhage
- multidrug resistant
- pain management
- replacement therapy