[Fecal microbiota transplantation for graft-versus-host disease in children and adults: methods, clinical effects, safety].
Oleg Valerievich GoloshchapovA B ChukhlovinEvgeny A BakinOksana V StanevichR V KlementevaA A ShcherbakovA N ShvetsovM A SuvorovaS N BondarenkoMaxim Anatolievich KucherAlexander Dmitrievich KulaginLudmila Stepanovna ZubarovskayaIvan Sergeevich MoiseevPublished in: Terapevticheskii arkhiv (2020)
FMT in patients with refractory GI GVHD was associated with favorable clinical outcomes and recovery in certain marker bacterial populations. Multiplex PCR can be used to assess an engraftment of a donor microbiota. FMT in GI GVHD was not associated with life-threatening adverse events, but further studies are required to validate clinical efficacy.