Diagnostic accuracy of automated Lumipulse plasma pTau-217 in Alzheimer's disease: a real-world study.
Giordano CecchettiFederica AgostaGiulia RugarliEdoardo Gioele SpinelliAlma GhirelliMatteo ZavarellaIlaria BottaleFrancesca OrlandiRoberto SantangeloFrancesca CasoGiuseppe MagnaniMassimo FilippiPublished in: Journal of neurology (2024)
The findings confirm that Lumipulse plasma pTau-217 offers superior diagnostic accuracy for reflecting CSF A/T status. Plasma pTau-217 emerged as an accurate standalone biomarker of AD neuropathology across MCI and dementia stages. The study underscores the utility of automated Lumipulse assays, promoting their integration into routine diagnostic workflows to facilitate early and accurate AD detection.