Bicarbonate ion transport by the electrogenic Na+ /HCO3 - cotransporter, NBCe1, is required for normal electrical slow-wave activity in mouse small intestine.
Wenchang ZhaoLiwen ZhangLeonid G ErmilovMaria Gabriela Colmenares AguilarDavid R LindenSeth T EisenmanMichael F RomeroGianrico FarrugiaLei ShaSimon J GibbonsPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2021)
These studies demonstrate a major role for Na+ /HCO3 - cotransport by NBCe1 in electrical activity of mouse small intestine and indicated that regulation of intracellular acid:base homeostasis contributes to generation of normal pacemaker activity in the gastrointestinal tract.
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