Effect of Nonadherence on Levetiracetam Pharmacokinetics and Remedial Dose Recommendations Using Monte Carlo Simulations.

Published in: European journal of drug metabolism and pharmacokinetics (2022)

The appropriate remedial dosage regimen for one and two consecutive missed doses of LEV have been proposed. These remedial regimens, however, should be applied with clinicians' judgment based on the clinical status of the patients.

Keyphrases

monte carlo
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
palliative care
molecular dynamics
clinical practice